Plasma Fibrinogen Levels as a Predictor of Bleeding Risk
Plasma fibrinogen plays a central role in hemostasis, serving as a precursor to fibrin and contributing to platelet aggregation and clot stability. As a result, plasma fibrinogen concentration has emerged as a clinically meaningful biomarker for assessing bleeding...
Effect of Neuraxial Anesthesia on Sensory, Motor, and Autonomic Nerves
Neuraxial anesthesia, which encompasses spinal and epidural techniques, remains a cornerstone of modern anesthetic practice, particularly for surgeries involving the lower abdomen, pelvis, and lower extremities. Its mechanism of action involves the administration of...
Strategies to Extend the Duration of Nerve Blocks for Total Knee Arthroplasty
In total knee arthroplasty, regional anesthesia provides effective analgesia, reduces opioid consumption, and facilitates early mobilization. However, the limited duration of single-shot peripheral nerve blocks can pose issues for some surgeries, particularly in the...
Paradoxical Agitation with Midazolam
Midazolam is a benzodiazepine that induces sedation and anesthesia. It is commonly used to reduce anxiety before an operation and as an induction agent of general anesthesia. It can also help in the management of acute seizures.1 According to one estimate, midazolam...
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